
Scientific Programme
Auditorium 2 - Fundação Calouste Gulbenkian
Thursday, 10 May 2018
9.00 - Opening Session – Jorge Soares, Leonor David and Luís Costa
Plenary Lectures
Chairs: João Barata, Leonor David
09.30 – 10.15 – EACR Lecture – Anton Berns (President of EACR; Netherlands Cancer Institute)
Mouse models of lung cancer. What do they teach us?
10.15 – 11.00 - ASEICA Lecture – Xosé Bustelo (Vice-President of ASEICA; Universidad de Salamanca)
Bivalents roles of Vav oncoproteins in cancer: Genetic evidence and potential translation to human settings
11.00 – 11.30 – Coffee break
11.30 – 13.00 - Symposium I – Invasion and Metastasis
Chairs: Joana Paredes and Bruno Costa Silva
11.30 – 11.45 – Selected oral presentation - Paulo de Sepúlveda (CRCM, INSERM)
Unexpected tumor suppression function for FES tyrosine kinase in cancer
11.45 – 12.00 – Selected oral presentation - Carlos Custódia (IMM)
Patient-derived xenograft models of brain metastases for translational medicine
12.00 - 12.30 - Invited speaker: Susana Godinho (Barts Cancer Institute)
Oxidative stress in cells with extra centrosomes drives non-cell autonomous invasion
12.30 – 13.00 - Invited speaker: Sandra Swain (Georgetown University Medical Center)
The path to success in HER2-positive breast cancer
13.00 – 14.00 – Lunch
14.00 – 16.00 – Poster Session - Rooms 1, 2 and Hall
16.00 – 17.30 - Symposium II – Therapy Resistance
Chairs: João Nuno Moreira and Isabel Fernandes
16.00 -16.30 - Invited speaker: Peter Nelson (Fred Hutchinson Cancer Research Center)
Therapy Resistance: The Emergence of New Cancer Species Evolving Through Treatment Pressures
16.30 – 17.00 Invited speaker: Daniel Peeper (Netherlands Cancer Institute)
Towards rational combinatorial cancer treatment — a functional genomics approach
17.00 – 17.15- Selected oral presentation - Vânia Palma Roberto (UAlg)
TERT methylation: a potential diagnostic and prognostic tool for the management of colorectal cancer
17.15 – 17.30 – Selected oral presentation - Raquel Cruz-Duarte (IMM)
PLCγ1 Mediates Resistance to Anti-EGFR Therapy in Metastatic Colorectal Cancer
17.30 – 18.00 – Coffee break
18.00 – 19.00 - ASPIC General Assembly
20.00 - Congress Dinner
Friday, 11 May 2018
09.00 – 10.15 – Parallel workshops
WORKSHOP 1 - The importance of biomarker validation to increase success in cancer drug development and approval. (Organization: Júlio Oliveira, Lúcio Lara Santos, André Albergaria) - Room 3
WORKSHOP 2 - Consortium Kick-off Meeting: Building and promoting Excellence in Cholangiocarcinoma Sciences in Portugal. (Organization: Júlio Oliveira, Lúcio Lara Santos, André Albergaria) - Auditorium 3
WORKSHOP 3 - Presentation of the European Reference Network GENTURIS - Genetic tumour risk syndromes: opportunities to improve health care for patients with hereditary cancer syndromes in Europe. (Organization: Carla Oliveira and Tamara Hussong Milagre (patient association EVITA) - Auditorium 2
Speaker: Nicoline Hoogerbrugge (GENTURIS President)
ASPIC Plenary Lecture
Chairs: Luís Costa and Fátima Vaz
10.15 - 11.00 - Carlos Caldas (University of Cambridge)
A systems level panoramic view of breast cancer
11.00 – 11.30 – Coffee break
11.30 – 13.00 - Symposium III - New technologies / New achievements - Part 1
Chairs: Raquel Seruca and Lúcio Lara Santos
11.30 – 11.45 - Selected oral presentation - Celine Gonçalves (ICVS - UMinho)
Functional and prognostic relevance of WNT6 in human glioblastoma
11.45 – 12.00 – Selected oral presentation - Maria José Oliveira (i3S/INEB)
Reprogramming antigen-presenting cells: a chitosan/γ-PGA nanoparticles for anticancer therapy
12.00 – 12.30 - Invited speaker: Luís Almeida (Blueclinical, Universidade do Porto)
Oncological R&D Pipeline – booming of mechanisms and targets
12.30 – 13.00 – Invited speaker: J. Iñaki Martin-Subero (IDIBAPS)
Decoding the epigenome of normal and neoplastic B cells: biological and clinical insights
13.00 – 14.00 – Lunch
14.00 – 15.30 - Symposium IV – Metabolism and Cancer
Chairs: Ana Preto and Manuel Sobrinho Simões
14.00 - 14.30 - Invited speaker: Michael P. Lisanti (University of Salford)
Cancer Stem Cells (CSCs): New Approaches to their Identification and Eradication
14.30 - 15.00 – Invited speaker: Carla Martins (University of Cambridge)
Targeting the metabolic dependencies of mutant Kras lung tumours
15.00 – 15.15 - Selected oral presentation - Soraia Melo (i3S/Ipatimup)
A novel regulation mechanism underlying loss of E-cadherin expression in Hereditary Diffuse Gastric Cancer families
15.15 – 15.30 – Selected oral presentation - Bruno A. Cardoso (IMM)
CASZ1 is overexpressed in T-cell acute lymphoblastic leukemia and promotes cell transformation and tumor growth via PI3K-mTOR
15.30 – 16.00 – Coffee break
16.00 – 17.30 – Symposium V – Host and Cancer (Immunotherapy)
Chairs: Sofia Braga and José Carlos Machado
16.00 – 16.30 – Invited Speaker: Christian Blank (Netherlands Cancer Institute)
Neo-adjuvant checkpoint inhibition – the pathway towards personalized immunotherapy
16.30 – 17.00 – Invited speaker: Cora Sternberg (San Camillo Forlanini Hospital)
Immunotherapy in the treatment of Urothelial Cancer (UC)
17.00 - 17.30 - Symposium III - New technologies / New achievements - Part 2
17.00 - 17.30 - Invited speaker: Leon Alkalai (NASA) - (Webex conference)
The Future of Robotic Space Exploration: from our Solar System to Interstellar Exploration. How Medicine can benefit from that knowledge?
17.30 – 18.00 - EACR awards and closing – Carlos Caldas, José Luís Passos Coelho, Jorge Soares and Luís Costa